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Video: Smallpox: What Every Clinician Should Know

Smallpox disease was eradicated from earth in 1977. Because of concerns that smallpox virus could be used as an agent of bioterrorism, providers should be familiar with the disease and the vaccine to prevent it. This video presents information on virology, epidemiology, clinical features and diagnosis of smallpox, and the characteristics and use of smallpox vaccine.  

This training was developed for use with Dryvax® vaccine. Another brand of vaccine, ACAM2000™, has been licensed that, while nearly identical in administration and technique, does have some minor differences; most notably the change to 15 insertions for both primary and secondary vaccinees. Healthcare providers are advised to familiarize themselves with the information in the package insert before beginning vaccination clinics:

Order the video

To order videotapes, please contact the Public Health Foundation online at ( or call 1-877-252-1200.

Or watch the video in segments

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Non-Closed Caption
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Program Introduction (7min 20 sec) view view
Smallpox and Bioterrorism Background (3 min 7 sec) view view
Smallpox Virus (3 min 16 sec) view view
Smallpox Clinical Features (12 min 8 sec) view view
Diagnosis and Confirmation (22 min 14 sec) view view
Smallpox Isolation and Management (3 min 13 sec) view view
Smallpox Epidemiology (4 min 4 sec) view view
Smallpox Eradication (54 min 39 sec) view view
Smallpox Vaccine (33 min 41 sec) view view
Response Plan (6 min 31 sec) view view
Summary (1 min 44 sec) view view
Resources (2 min 43 sec) view view
Contact Us: - Prepare. Plan. Stay Informed. The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC-INFO

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