Smallpox Overview for Clinicians

CDC Clinician Information Line: 877-554-4625

This page is intended to provide core smallpox materials to clinicians. This is not a complete listing of CDC’s resources. A more comprehensive listing can be found on the smallpox topic pages on this website. Information for the general public can be found on the Smallpox Disease and Smallpox Vaccine pages.

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Smallpox Disease

Diagnosis and Evaluation

Vaccination Contraindications

Normal Vaccination Reactions/Take Evaluations

Vaccination Adverse Reactions and Management


Specific Reactions

Thumbnail image for Erythema Multiforme
Erythema Multiforme
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Bacterial Infection
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Accidental Implantation
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Vaccinia Keratitis
Thumbnail image for Eczema Vaccinatum
Eczema Vaccinatum
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Generalized Vaccinia
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Congenital Vaccinia
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Progressive Vaccinia
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Vaccine Administration

Vaccination Recommendations and Policy

Patient Education

Frequently Asked Questions

More Information

Page last reviewed: November 18, 2015