Smallpox Vaccination: Adverse Events
Information for the public can be found on the Smallpox Vaccine page.
On this page:
General Resources for Professionals
- Q & A: Adverse Events and Vaccine Safety
Frequently asked questions and answers for professionals
- Clinical Evaluation Tools for Smallpox Vaccine Adverse Reactions
Tools for clinicians
- Fact Sheet: Medical Management of Smallpox Vaccine Adverse Reactions
For clinicians. Includes information on the two medications (Vaccinia Immune Globulin & Cidofovir) that may help persons who have certain serious reactions to the vaccine Updated! March 10, 2008
- Fact Sheet:
Investigational Vistide® (Cidofovir) Information
Drugs used to treat reactions to the smallpox vaccine Updated! March 10, 2008
- Fact Sheet:
Investigational Vaccinia Immune Globulin (VIG) Information
Drugs used to treat reactions to the smallpox vaccine Updated! March 10, 2008
- Fact Sheet: Smallpox (Vaccinia) Vaccine Adverse Event Reporting
For clinicians
- Reactions to Smallpox Vaccinations
Graphic clinical images of reactions to smallpox vaccinations.
- Fact Sheet: Adverse Reactions Following Smallpox Vaccination
For clinicians
-
Guidance for the Healthcare Community Concerning Section 304 of the Homeland Security Act
From Smallpox Q&A
- Algorithm for Evaluating Suspected Vaccinia Vaccination (Smallpox Vaccination) Pericarditis-Myocarditis
(103 KB/7 pages)
DoD Vaccine Healthcare Center (VHC), Version 21 July 05
The preparation of the Smallpox Myopericarditis Algorithm was due to the efforts of the many individuals affiliated with the VHC Network.
Registries
- Countermeasures Injury Compensation Program
A Federal program, the Countermeasures Injury Compensation Program, has been created under the PREP Act to help pay for medical care and other specific expenses of certain individuals who have a serious reaction to this vaccine. If you have a reaction to the vaccine your ability to sue may be limited by law. For more information, visit the program's website at www.hrsa.gov/countermeasurescomp, or call 1-888-275-4772. - Interim Protocol for Blood and/or Vaccinia Virus Exposures (393 KB/14 pages)
Protocol for Investigating and Reporting Blood and/or Vaccinia Virus Exposures During Smallpox Vaccination
Feb 24, 2003
(last reviewed Feb 21, 2006) - Notice to Readers: National Smallpox Vaccine in Pregnancy Registry
MMWR 2003 Mar 28;52(12):256.
PDF (1.21 MB/28 pages)
References
-
Smallpox Vaccination & Adverse Reactions: Guidance for Clinicians
MMWR 2003 Feb 21;52(RR04):1-28.
PDF (5.36 MB/32 pages) - Smallpox Vaccination & Adverse Reactions: A Teaching Slide Set
Slide set that reviews key points in the MMWR report Smallpox Vaccination & Adverse Events: Guidance for clinicians
-
Notice to Readers: Supplemental Recommendations on Adverse Events Following Smallpox Vaccine in the Pre-Event Vaccination Program: Recommendations of the ACIP
PDF (1.08 MB/28 pages) -
Update: Cardiac-Related Events During the Civilian Smallpox Vaccination Program — United States, 2003
MMWR 2003 May 30;52(21);492-496.
PDF (267 KB/24 pages) - Chart: Smallpox Vaccine Adverse Event Rates, 1968
Get email updates
To receive email updates about this page, enter your email address:
Contact Us:
- Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333 - 800-CDC-INFO
(800-232-4636)
TTY: (888) 232-6348 -
New Hours of Operation
8am-8pm ET/
Monday-Friday
Closed Holidays - cdcinfo@cdc.gov
